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Invitrogen™ GPR143 Polyclonal Antibody
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Catalog No. PIPA5120094
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100 μL
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PIPA5120094 100 μL
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Catalog No. PIPA5120094 Supplier Invitrogen™ Supplier No. PA5120094
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Description

Rabbit Polyclonal Antibody

Positive test controls include: U-251MG, BT-474, SW480, Mouse liver, Mouse kidney, Rat kidney. The target is usually found in the following locations: Apical cell membrane, Golgi apparatus, Lysosome membrane, Melanosome membrane, Multi-pass membrane protein. Immunogen sequence: TGCSLGFQSP RKEIQWESLT TSAAEGAHPS PLMPHENPAS GKVSQVGGQT SDEALSMLSE GSDASTIEIH TASESCNKNE GDPALPTHGD L.

Ocular albinism type 1 protein is a conserved integral membrane protein with seven transmembrane domains. It is expressed in the eye and epidermal melanocytes. Defects in GPR143 are the cause of ocular albinism type 1 (OA1); also known as Nettleship-Falls type ocular albinism. OA1 is an X-linked disorder characterized by severe impairment of visual acuity, retinal hypopigmentation and the presence of macromelanosomes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GPR143
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.98 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene GPR143
Gene Accession No. P51810, P70259
Gene Alias G protein-coupled receptor 143; GPR143; G-protein coupled receptor 143; homolog of human ocular albinism 1 (Nettleship-Falls); MOA1; NYS6; OA1; ocular albinism 1; ocular albinism type 1 protein; Ocular albinism type 1 protein homolog; RGD1565799
Gene Symbols GPR143
Host Species Rabbit
Immunogen Recombinant protein (or fragment).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18241, 302619, 4935
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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