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Invitrogen™ GPR160 Polyclonal Antibody
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Catalog No. PIPA132672
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25 μg
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Catalog No. Quantity
PIPA132672 25 μg
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Catalog No. PIPA132672 Supplier Invitrogen™ Supplier No. PA132672
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Description

Rabbit Polyclonal Antibody

PA1-32672 detects GPCR GPCR150 from human samples.

GPR160, part of the Class A family of G protein-coupled receptors (GPCRs), is prominently expressed in mouse embryonic stem cells and has been associated with various human solid tumors, particularly prostate cancer. The gene's expression contributes to the self-renewal and pluripotency of stem cells by participating in critical signaling pathways, including the JAK/STAT pathway, which is crucial for maintaining the stem cell cycle. High levels of GPR160 expression are observed in prostate cancer, though its role in disease progression is independent of the CARTp-mediated signaling pathway. Investigations into GPR160 have revealed its potential as a biomarker for prostate cancer. Additionally, it regulates mycobacteria entry into macrophages, implicating its functionality in immune responses. The gene's mechanisms of action, especially within cancer contexts, are subjects of ongoing research aimed at understanding its precise contributions to cellular proliferation and disease phenotypes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GPR160
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide
Gene GPR160
Gene Accession No. Q9UJ42
Gene Alias 1700025D19Rik; G protein-coupled receptor 160; GPCR1; GPCR150; GPR160; G-protein coupled receptor GPCR1; hGPCR1; probable G-protein coupled receptor 160; putative G protein-coupled receptor
Gene Symbols GPR160
Host Species Rabbit
Immunogen Synthetic 20 amino acid peptide from 1st transmembrane domain of human GPR160.
Purification Method Antigen affinity chromatography
Quantity 25 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 26996
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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