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Invitrogen™ GPR17 Monoclonal Antibody (OTI17C1)
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Catalog No. PIMA527501
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100 μL
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Catalog No. Quantity
PIMA527501 100 μL
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Catalog No. PIMA527501 Supplier Invitrogen™ Supplier No. MA527501
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Description

Mouse Monoclonal Antibody

GPR17 Monoclonal Antibody for IHC (P)

The G-protein-coupled receptor (GPCR) superfamily is comprised of an estimated 600-1,000 members and is the largest known class of molecular targets with proven therapeutic value. GPR17 is an orphan G protein-coupled receptor involved in orchestration of oligodendrocyte differentiation and myelination in the central nervous system. GPR17 is expressed in brain, kidney, heart and umbilical vein endothelial cells. GPR17 has dual specificity for uracil nucleotides and cysteinyl leukotrienes and signals through G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and cysteinyl leukotrienes following ischemia.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GPR17
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone OTI17C1
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene GPR17
Gene Accession No. Q13304
Gene Alias AI853548; DKFZp686M18273; G protein-coupled receptor 17; Gpr17; gpr17 {ECO:0000312; G-protein coupled receptor 17; P2Y-like receptor; R12; RGD:1589785}; UDP/CysLT receptor; Uracil nucleotide/cysteinyl leukotriene receptor; Y12546; Z94155
Gene Symbols GPR17
Host Species Mouse
Immunogen Synthetic peptide within Human GPR17 C-terminal.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2840
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2b
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