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GPR17 Mouse anti-Human, Clone: OTI10B8, lyophilized, TrueMAB™
SDP

Mouse Monoclonal Antibody

Supplier:  OriGene CF811748

Encompass_Preferred

Catalog No. 50-167-0822


May include imposed supplier surcharges.
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Description

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

The G-protein-coupled receptor (GPCR) superfamily is comprised of an estimated 600-1,000 members and is the largest known class of molecular targets with proven therapeutic value. GPR17 is an orphan G protein-coupled receptor involved in orchestration of oligodendrocyte differentiation and myelination in the central nervous system. GPR17 is expressed in brain, kidney, heart and umbilical vein endothelial cells. GPR17 has dual specificity for uracil nucleotides and cysteinyl leukotrienes and signals through G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and cysteinyl leukotrienes following ischemia.
Specifications

Specifications

GPR17
Monoclonal
Unconjugated
GPR17
G protein-coupled receptor 17
Mouse
Affinity Chromatography
RUO
2840
-20° C, Avoid Freeze/Thaw Cycles
Lyophilized
Immunohistochemistry (Paraffin)
OTI10B8
PBS with 8% trehalose and no preservative; pH 7.3
Q13304
GPR17
Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human GPR17 C-terminal. The exact sequence is proprietary.
100 μg
Primary
Human
Antibody
IgG1
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