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Invitrogen™ GPR17 Polyclonal Antibody
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Catalog No. PIPA5120874
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100 μL
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PIPA5120874 100 μL
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Catalog No. PIPA5120874 Supplier Invitrogen™ Supplier No. PA5120874
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Description

Rabbit Polyclonal Antibody

Positive test controls include: Mouse spinal cord, Mouse brain, Rat brain. Immunogen sequence: MSKRSWWAGS RKPPREMLKL SGSDSSQSMN GLEVAPPGLI TNFSLATAEQ CGQETPLENM LFASFYLLDF ILALVGNTLA LWLFIRDHKS GTPA.

The G-protein-coupled receptor (GPCR) superfamily is comprised of an estimated 600-1,000 members and is the largest known class of molecular targets with proven therapeutic value. GPR17 is an orphan G protein-coupled receptor involved in orchestration of oligodendrocyte differentiation and myelination in the central nervous system. GPR17 is expressed in brain, kidney, heart and umbilical vein endothelial cells. GPR17 has dual specificity for uracil nucleotides and cysteinyl leukotrienes and signals through G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and cysteinyl leukotrienes following ischemia.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GPR17
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.61 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene GPR17
Gene Accession No. Q09QM4, Q13304, Q6NS65
Gene Alias AI853548; DKFZp686M18273; G protein-coupled receptor 17; Gpr17; gpr17 {ECO:0000312; G-protein coupled receptor 17; P2Y-like receptor; R12; RGD:1589785}; UDP/CysLT receptor; Uracil nucleotide/cysteinyl leukotriene receptor; Y12546; Z94155
Gene Symbols GPR17
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-94 of human GPR17 (NP_005282.1).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2840, 574402, 767613
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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