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GPR17 Mouse anti-Human, Clone: OTI17C1, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA527501

Catalog No. PIMA527501


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Description

Description

Members of the G protein coupled receptor (GPCR) superfamily contain 7 trans membrane domains and transduce extracellular signals through heterotrimeric G proteins. The organization of the GPR17 gene differs from that of many other GPCRs in that the open reading frame is distributed on 2 exons; an additional exon contains the 5 prime untranslated region. Human GPR17 is expressed as 2.3 and 6.3 kb mRNAs exclusively in brain. The 2 transcripts appear to represent alternatively polyadenylated variants. Based on protein sequence homology and the conservation of certain key residues, GPR17 appears to be closely related to the P2Y family of GPCRs. There are two isoforms.
Specifications

Specifications

GPR17
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Q13304
GPR17, G protein-coupled receptor 17, G-protein coupled receptor 17, R12, P2Y-like receptor, UDP/CysLT receptor, Uracil Nucleotide/Cysteinyl Leukotriene receptor
Mouse
IgG2b
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
2840
Immunohistochemistry (Paraffin)
OTI17C1
Unconjugated
GPR17
Liquid
GPR17
Synthetic peptide within Human GPR17 C-terminal.
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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