Invitrogen™ GPR176 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA3046

Catalog No. PIPA3046

Description

GPR176 is in the G protein-coupled receptor family and are cell surface receptors involved in responses to hormones, growth factors, and neurotransmitters. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Bovine, Dog, Bat, Horse, Stickleback, Zebrafish (100%). GPR176 exists in different glycosylated forms.

G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR176 (G protein-coupled receptor 176), also known as HB-954, GPR or Gm1012, is a 515 amino acid multi-pass membrane protein belonging to the G-protein coupled receptor 1 family. Expressed in brain and spleen, with trace expression in kidney, GPR176 functions as an orphan receptor that is thought to play a role in signaling events throughout the cell. Containing four N-glycosylation sites, seven transmembrane domains and a large C-terminal cytosolic domain, GPR176 is encoded by a gene mapping to human chromosome 15q14.

Specifications

• Antigen: GPR176
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GPR176
• Gene Alias: Agr9; G protein-coupled receptor 176; Gm1012; Gpr; GPR176; G-protein coupled receptor 176; G-protein coupled receptor AGR9; HB954; HB-954; probable G-protein coupled receptor 176; putative G protein coupled receptor; RBU-15
• Host Species: Rabbit
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: Conc. Not Determined
• Formulation: Whole Serum with 0.05% sodium azide
• Gene Accession No.: Q14439, Q80WT4
• Gene Symbols: GPR176
• Immunogen: KLH conjugated COOH-terminal amino acids of 496-515 (RVERKMSRNNKVSIFPKVDS).
• Regulatory Status: RUO
• Gene ID (Entrez): 11245, 381413
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid