Invitrogen™ GPR27 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA533685

Catalog No. PIPA533685

Description

Percent identity with other species by BLAST analysis: Human, Mouse, Rat, Elephant, Panda (100%); Opossum (89%). For IHC(P), use proteinase K antigen retrieval. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.

G protein coupled receptors (GPCRs) are a large family of receptors that have a similar structure characterized by 7 transmembrane domains. Activation of GPCRs by extracellular stimuli such as neurotransmitters, hormones, or light induces an intracellular signaling cascade mediated by heterotrimeric GTP-binding proteins, or G proteins. The 375 amino acid GPCR GPR27 protein contains several features of the GPCR family, including 7 transmembrane domains, potential N linked glycosylation sites in the N terminal extracellular domain, and conserved cysteine residues, which may form a disulfide bridge, in the first and second extracellular loops.

Specifications

• Antigen: GPR27
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GPR27
• Gene Alias: G protein-coupled receptor 27; GPR27; Probable G-protein coupled receptor 27; SREB1; Super conserved receptor expressed in brain 1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 14761, 2850, 65275
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 1 mg/mL
• Formulation: PBS with 0.1% sodium azide
• Gene Accession No.: O54897, Q9JJH3, Q9NS67
• Gene Symbols: GPR27
• Immunogen: Synthetic 19 amino acid peptide from 3rd cytoplasmic domain of human GPR27.
• Quantity: 50 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG