GPR31 Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-2949	100 μL

Catalog No. 50-198-2949 Supplier Bioss Supplier No. BS13530R

Description

Rabbit Polyclonal Antibody

The G-protein-coupled receptor (GPCR) superfamily is comprised of an estimated 600-1,000 members and is the largest known class of molecular targets with proven therapeutic value. GPR31 is a high-affinity receptor for 12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid (12-S-HETE). 12-(S)-HETE is an arachidonic acid metabolite secreted by platelets and tumor cells, and known to induce endothelial cells retraction allowing invasive cell access to the subendothelial matrix, which is a critical step for extravasation or metastasis. Ligand-binding leads to activation of MAPK and NF-kappa-B pathways.

Specifications

• Antigen: GPR31
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin)
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: GPR31
• Gene Accession No.: O00270
• Gene Alias: 12-(S)-HETE acid receptor; 12-(S)-HETE receptor; 12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid (HETE) receptor; 12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid receptor; 12-HETER; bA517H2.2 (G protein-coupled receptor 31); G protein-coupled receptor 31; GPR31; G-protein coupled receptor 31; HETER; HETER1; hydroxyeicosatetraenoic (HETE) acid receptor 1; probable G-protein coupled receptor 31; TCP10C
• Gene Symbols: GPR31
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide derived from human G protein coupled receptor 31.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 2853
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG