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Invitrogen™ GPR39 Polyclonal Antibody
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Catalog No. PIPA3027
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PIPA3027 100 μL
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Catalog No. PIPA3027 Supplier Invitrogen™ Supplier No. PA3027
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Rabbit Polyclonal Antibody

IHC (P) analysis shows positive staining of GPR39 in human enteric ganglion. WB analysis shows GPR39 in glycoprotein-enriched fractions from mock transfected or GPR39 overexpressing 293 cells. The GPR39 antiserum showed specific detection of GPR39 over other tested GPRs. While GPR39 has a theoretical MW of ~ 51kD, the observed band in a WB runs at ~72kD due to enrichment of the glycosylated receptor.

The G-protein-coupled receptor (GPCR) superfamily is comprised of an estimated 600-1,000 members and is the largest known class of molecular targets with proven therapeutic value. G protein-coupled receptor 39 is an orphan receptor in the Ghrelin family pathway. Various studies have shown that GPR39 plays important roles in hypertension, adipogenesis and that overexpression of GPR39 contributes to malignant development of human esophageal squamous cell carcinoma.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GPR39
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation whole serum with 0.05% sodium azide
Gene GPR39
Gene Accession No. O43194
Gene Alias 4933415E13Rik; G protein-coupled receptor 39; GPR39; G-protein coupled receptor 39
Gene Symbols GPR39
Host Species Rabbit
Immunogen KLH conjugated Cys-NSGAKPANSAAENGFQEHEV.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2863
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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