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Tocris Bioscience™ GPR52 Comp-43

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Quantity:
10 mg
50 mg
Description
GPR52 Comp-43 is a GPR52 receptor antagonist (IC50 = 0.63 μM). The use of GPR52 Comp-43 in animal models of Huntington's Disease leads to degradation and reduction of soluble and aggregated mutant huntingtin protein in the striatum. It also reduces neuronal loss, promotes neuronal survival and improves motor functions in vivo. GPR52 Comp-43 is active in vitro and brain penetrant.
Specifications
Specifications
Chemical Name or Material | (2 E)-5-Phenyl-1-(2-thienyl)-2-penten-1-one |
CAS | 1239987-91-7 |
Quantity | 50 mg |
Target | Orphan 7-TM Receptor Antagonists |
Molecular Formula | C15H14OS |
Purity | 0.98 |
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