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Invitrogen™ GPR65 Polyclonal Antibody
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Catalog No. PIPA533754
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50 μg
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Catalog No. Quantity
PIPA533754 50 μg
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Catalog No. PIPA533754 Supplier Invitrogen™ Supplier No. PA533754
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Description

Rabbit Polyclonal Antibody

Percent identity with other species by BLAST analysis: Human, Gorilla, Monkey (100%) Gibbon, Marmoset (95%) Rabbit (84%).

GPR65 also known as TDAG8 is a transmembrane protein belonging to the G protein coupled receptor super family with 337-amino acid and 90% similarity and 81% identity in the 7 transmembrane domains of its mouse homolog. It has 3 potential N-linked glycosylation sites and is expressed predominantly in lymphoid organs and cancer tissues with increased expression during activation-induced death of T-cell hybridomas. Two major transcripts of 4.5 kb and 1.8 kb are found in peripheral blood leukocytes and functions as a novel proton-sensing receptor. It couples to adenylyl cyclase and psychosine and is also actively involved in the establishment of immunological autotolerance. GPR65 has a role in cellular transformation by RhoA activation and actin rearrangement under conditions accompanying tissue acidosis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GPR65
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide
Gene GPR65
Gene Accession No. Q8IYL9
Gene Alias Dig1; G protein-coupled receptor 65; Gpcr25; Gpr65; G-protein coupled receptor 25; G-protein coupled receptor 65; hTDAG8; Psychosine receptor; T cell death associated protein 8; T-cell death-associated gene 8 protein; TDAG8
Gene Symbols GPR65
Host Species Rabbit
Immunogen Synthetic 19 amino acid peptide from 3rd cytoplasmic domain of human GPR65.
Purification Method Antigen affinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8477
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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