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Invitrogen™ GPR65 Polyclonal Antibody
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Catalog No. PIPA565873
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100 μL
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PIPA565873 100 μL
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Catalog No. PIPA565873 Supplier Invitrogen™ Supplier No. PA565873
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: ETGRYDMWNIL KFCTGRCNTS QRQRKRILSV STKDTMELEV Highest antigen sequence identity to the following orthologs - mouse 61%, rat 63%.

GPR65 also known as TDAG8 is a transmembrane protein belonging to the G protein coupled receptor super family with 337-amino acid and 90% similarity and 81% identity in the 7 transmembrane domains of its mouse homolog. It has 3 potential N-linked glycosylation sites and is expressed predominantly in lymphoid organs and cancer tissues with increased expression during activation-induced death of T-cell hybridomas. Two major transcripts of 4.5 kb and 1.8 kb are found in peripheral blood leukocytes and functions as a novel proton-sensing receptor. It couples to adenylyl cyclase and psychosine and is also actively involved in the establishment of immunological autotolerance. GPR65 has a role in cellular transformation by RhoA activation and actin rearrangement under conditions accompanying tissue acidosis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GPR65
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene GPR65
Gene Accession No. Q8IYL9
Gene Alias Dig1; G protein-coupled receptor 65; Gpcr25; Gpr65; G-protein coupled receptor 25; G-protein coupled receptor 65; hTDAG8; Psychosine receptor; T cell death associated protein 8; T-cell death-associated gene 8 protein; TDAG8
Gene Symbols GPR65
Host Species Rabbit
Immunogen Recombinant Human GPR65. Recombinant protein control fragment (Product #RP-106544).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8477
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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