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Invitrogen™ GPR77 Polyclonal Antibody
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Catalog No. PIPA5110816
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100 μL
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PIPA5110816 100 μL
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Catalog No. PIPA5110816 Supplier Invitrogen™ Supplier No. PA5110816
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: NDSVSYEYGD YSDLSDRPVD CLDGACLAID PLR Highest antigen sequence indentity to the following orthologs: Rat - 44%, Mouse - 39%.

C5AR2 is an orphan member that belongs to anaphylatoxin receptor family. It is a seven transmembrane G-protein-coupled receptor consisting of an N-terminal N-glycosylation site, several conserved cysteines and several potential C-terminal phosphorylation sites. It binds to C5a and C5a-des-Arg and serves as a highly regulated scavenger receptor with a negative modulatory influence on C5aR-mediated inflammation. Northern Blot analysis suggests it is co- expressed along with C5aR in different tissues and cells including neutrophils/macrophages, mast cells, dendritic cells, brain, lung, heart, kidney, liver, ovary and testis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GPR77
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.10 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene C5AR2
Gene Accession No. Q9P296
Gene Alias C5a anaphylatoxin chemotactic receptor 2; C5a anaphylatoxin chemotactic receptor C5L2; C5AR2; C5L2; Complement component 5a receptor 2; G protein-coupled receptor 77; G protein-coupled receptor C5L2; GPF77; GPR77; G-protein coupled receptor 77
Gene Symbols C5AR2
Host Species Rabbit
Immunogen Recombinant Protein corresonding to Human GPR77. Recombinant protein control fragment (Product #RP-90864).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 27202
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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