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GPR77 Polyclonal Antibody, Invitrogen™

Catalog No. PIPA521307
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100 μL
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PIPA521307 100 μL
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Catalog No. PIPA521307 Supplier Thermo Scientific Supplier No. PA521307

Description

Rabbit Polyclonal Antibody

Recommended positive controls: 293T, A431, H1299, HeLa, Molt-4, Raji. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

C5AR2 is an orphan member that belongs to anaphylatoxin receptor family. It is a seven transmembrane G-protein-coupled receptor consisting of an N-terminal N-glycosylation site, several conserved cysteines and several potential C-terminal phosphorylation sites. It binds to C5a and C5a-des-Arg and serves as a highly regulated scavenger receptor with a negative modulatory influence on C5aR-mediated inflammation. Northern Blot analysis suggests it is co- expressed along with C5aR in different tissues and cells including neutrophils/macrophages, mast cells, dendritic cells, brain, lung, heart, kidney, liver, ovary and testis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GPR77
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene C5AR2
Gene Accession No. Q9P296
Gene Alias C5a anaphylatoxin chemotactic receptor 2; C5a anaphylatoxin chemotactic receptor C5L2; C5AR2; C5L2; Complement component 5a receptor 2; G protein-coupled receptor 77; G protein-coupled receptor C5L2; GPF77; GPR77; G-protein coupled receptor 77
Gene Symbols C5AR2
Host Species Rabbit
Immunogen Synthetic peptide corresponding to a region within amino acids 248 and 337 of GPR77 (Uniprot ID#Q9P296)
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 27202
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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