Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. PIPA597105

Invitrogen™ GPRC6A Polyclonal Antibody
GREENER_CHOICE

Catalog No. PIPA597105
Change view
Click to view available options
Quantity:
100 μL
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
PIPA597105 100 μL
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. PIPA597105 Supplier Invitrogen™ Supplier No. PA597105
Add to Cart
Add to Cart

Description

Rabbit Polyclonal Antibody

Immunogen sequence: IASDNWSTAT KITTIPNVKK IGKVVGFAFR RGNISSFHSF LQNLHLLPSD SHKLLHEYAM HLSACAYVKD TDLSQCIFNH SQRTLAYKAN KAIERNFVMR NDFLWDYAEP GLIHSIQLAV FALGYAIRDL CQARDCQNPN AFQPWELLGV LKNVTFTDGW NSFHFDAHGD LNTGYDVVLW KEINGHMTVT KMAEYDLQND VFIIPDQETK NEFRNLKQIQ SKCSKECSPG QMKKTTRSQH ICCYECQNCP ENHYTNQTDM PHCLLCNNKT HWAPVRSTMC FEKEVEYLNW N; Positive Samples: U-87MG, Mouse liver, Mouse lung, Mouse spleen; Cellular Location: Cell membrane, Multi-pass membrane protein.

GPRC6A is an Orphan-U GPCR with an unknown ligand. G-protein Coupled Receptors (GPCRs) comprise one of the largest families of signaling molecules with more thana thousandmembers currently predicted to exist. All GPCRs share a structural motif consisting of seven membrane-spanning helices, and exist in both active and inactive forms. An array of activating ligands participate in the conformation of GPCRs which leads to signaling via G-proteins and downstream effectors. Ongoing studies have also shown the vast series of reactions which participate in the negative regulation of GPCRs. This 'turn-off' activity has tremendous implications for the physiological action of the cell, and continues to drive pharmacological research for new drug candidates. Twoblockbuster drugs which have been developed as GPCR-targetedpharmaceuticals are Zyprexa (Eli Lilly) and Claritin (Schering-Plough) which have multi-billion dollar shares of the mental health and allergy markets, respectively.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GPRC6A
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.74 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene GPRC6A
Gene Accession No. Q5T6X5, Q70VB1, Q8K4Z6
Gene Alias bA86F4.3; G protein-coupled receptor class C group 6 member A; G protein-coupled receptor, class C, group 6, member A; G protein-coupled receptor, family C, group 6, member A; GPCR; Gprc6a; G-protein coupled receptor family C group 6 member A; G-protein coupled receptor GPCR33; hGPCR33; hGPRC6A; predicted with SOSUI analysis; seven transmembrane helix receptor
Gene Symbols GPRC6A
Host Species Rabbit
Immunogen Recombinant protein (or fragment).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 210198, 222545, 294394
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.