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Invitrogen™ GPX3 Polyclonal Antibody
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Catalog No. PIPA5120190
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100 μL
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PIPA5120190 100 μL
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Catalog No. PIPA5120190 Supplier Invitrogen™ Supplier No. PA5120190
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Description

Rabbit Polyclonal Antibody

Positive test controls include: HepG2, Mouse kidney, Mouse liver. The target is usually found in the following locations: Secreted. Immunogen sequence: QSRGQEKSKM DCHGGISG.

Glutathione peroxidases (Gpxs) are ubiquitously expressed proteins which catalyze the reduction of hydrogen peroxides and organic hydroperoxides by glutathione. There are several isoforms which differ in their primary structure and localization. The classical cytosolic/mitochondrial GPx1 (cGPx) is a selenium-dependent enzyme, first of the GPx family to be discovered. GPx2, also known as gastrointestinal GPx (GI-GPx), is an intracellular enzyme expressed only at the epithelium of the gastrointestinal tract. Extracellular plasma GPx (pGPx or GPx3) is mainly expressed by the kidney from where it is released into the blood circulation. Phospholipid hydroperoxide GPx4 (PH-GPx) expressed in most tissues, can reduce many hydroperoxides including hydroperoxides integrated in membranes, hydroperoxy lipids in low density lipoprotein or thymine. All mammalian GPx family members, except for the recently described Cys containing GPx3 and epididymis-specific secretory GPx (eGPx or GPx5) isoforms, possess selenocysteine at the active site (4-5).
TRUSTED_SUSTAINABILITY

Specifications

Antigen GPX3
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.85 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene Gpx3
Gene Accession No. P23764, P46412
Gene Alias AA960521; EGPx; extracellular glutathione peroxidase; extracellular GPx; glutathione peroxidase 3; glutathione peroxidase 3 (plasma); GPx; Gpx3; GPx-3; Gpxp; GPx-P; GSHPx-3; GSHPx-P; plasma form; plasma glutathione peroxidase; plasma GPx
Gene Symbols Gpx3
Host Species Rabbit
Immunogen Synthetic peptide.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14778, 64317
Target Species Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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