Invitrogen™ GPX4 Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA518545

Catalog No. PIPA518545

Description

This antibody is predicted to react with bovine, mouse, porcine and rat based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 16,000.

Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage. Human plasma glutathione peroxidase has been shown to be a selenium-containing enzyme and the UGA codon is translated into a selenocysteine. Through alternative splicing and transcription initiation, rat produces proteins that localize to the nucleus, mitochondrion, and cytoplasm. In humans, experimental evidence for alternative splicing exists; alternative transcription initiation and the cleavage sites of the mitochondrial and nuclear transit peptides need to be experimentally verified.

Specifications

• Antigen: GPX4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GPX4
• Gene Alias: glutathione peroxidase 4; GP-GPx4; Gpx4; gpx-4; GSHPx-4; HGNC:4556; MCSP; mtPHGPx; Phgpx; phospholipid hydroperoxidase; phospholipid hydroperoxide glutathione peroxidase; phospholipid hydroperoxide glutathione peroxidase, mitochondrial; phospholipid hydroperoxide glutathione peroxidase, nuclear; SMDS; snGPx; snPHGPx; sperm nuclei glutathione peroxidase; sperm nucleus glutathione peroxidase
• Host Species: Goat
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 2879, 29328, 625249
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Western Blot
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O70325, P36969, P36970
• Gene Symbols: GPX4
• Immunogen: Synthetic peptide sequence (EEPLVIEKDLPHY) corresponding to the C-terminus amino acids of GPX4 (aa 184-196).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG