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Invitrogen™ GRAF Polyclonal Antibody
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Catalog No. PIPA530967
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100 μL
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PIPA530967 100 μL
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Catalog No. PIPA530967 Supplier Invitrogen™ Supplier No. PA530967
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: A549, HepG2, HCT116. Predicted reactivity: Chicken (87%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Interaction of a cell with the extracellular matrix triggers integrin cell surface receptors to begin signaling cascades that regulate the organization of the actin-cytoskeleton. One of the proteins involved in these cascades is focal adhesion kinase. The protein encoded by this gene is a GTPase activating protein that binds to focal adhesion kinase and mediates the activity of the GTP binding proteins RhoA and Cdc42. Defects in this gene are a cause of juvenile myelomonocytic leukemia (JMML). Multiple transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GRAF
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene ARHGAP26
Gene Accession No. Q9UNA1
Gene Alias 1810044B20Rik; 2610010G17Rik; 4933432P15Rik; AI853435; Arhgap26; FLJ42530; GRAF; GRAF1; GTPase regulator associated with focal adhesion kinase; GTPase regulator associated with focal adhesion kinase pp125(FAK); Kiaa0621; mKIAA0621; oligophrenin-1-like protein; OPHN1L; OPHN1L1; Rho GTPase activating protein 26; rho GTPase-activating protein 26; Rho-type GTPase-activating protein 26
Gene Symbols ARHGAP26
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the C-terminus region of human GRAF. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23092
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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