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Invitrogen™ GRAF Polyclonal Antibody
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Catalog No. PIPA583259
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100 μL
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PIPA583259 100 μL
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Catalog No. PIPA583259 Supplier Invitrogen™ Supplier No. PA583259
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: RSSLHAVFSL LVNFVPCHPN LHLLFDRPEE AVHEDSSTPF RKAKALYACK AEHDSELSFT AGTVFDNVHP SQEPGWLE Highest antigen sequence indentity to the following orthologs: Rat - 56%, Mouse - 96%.

Interaction of a cell with the extracellular matrix triggers integrin cell surface receptors to begin signaling cascades that regulate the organization of the actin-cytoskeleton. One of the proteins involved in these cascades is focal adhesion kinase. The protein encoded by this gene is a GTPase activating protein that binds to focal adhesion kinase and mediates the activity of the GTP binding proteins RhoA and Cdc42. Defects in this gene are a cause of juvenile myelomonocytic leukemia (JMML). Multiple transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GRAF
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.4 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene ARHGAP26
Gene Accession No. Q9UNA1
Gene Alias 1810044B20Rik; 2610010G17Rik; 4933432P15Rik; AI853435; Arhgap26; FLJ42530; GRAF; GRAF1; GTPase regulator associated with focal adhesion kinase; GTPase regulator associated with focal adhesion kinase pp125(FAK); Kiaa0621; mKIAA0621; oligophrenin-1-like protein; OPHN1L; OPHN1L1; Rho GTPase activating protein 26; rho GTPase-activating protein 26; Rho-type GTPase-activating protein 26
Gene Symbols ARHGAP26
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human ARHGAP26. Recombinant protein control fragment (Product #RP-102650).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23092
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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