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Invitrogen™ GRAMD4 Polyclonal Antibody
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Catalog No. PIPA598543
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100 μg
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PIPA598543 100 μg
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Catalog No. PIPA598543 Supplier Invitrogen™ Supplier No. PA598543
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Description

Rabbit Polyclonal Antibody

GRAMD4 Polyclonal Antibody for Western Blot, IHC (P), ELISA

GRAMD4 also termed as Death inducing protein is a 578 amino-acid protein, which contains 1 GRAM domain. GRAMD4 as a multi-pass membrane protein localizes in the Mitochondrion membrane. Overexpression of GRAMD4 results in a strong apoptotic response involving caspase-3 activation and cleavage of poly (ADP-ribose)-polymerase. GRAMD4 is expressed in lung and in primary lung squamous cell carcinoma (LSCC) and shows up-regulation in mitochondria by E2F-1 after addition of 4-hydroxytamoxifen. This evidence suggests that GRAMD4 may be a potential target for cancer therapies.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GRAMD4
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 5 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene GRAMD4
Gene Accession No. Q6IC98, Q8CB44
Gene Alias 9930016O13; dA59H18.1; death-inducing protein; death-inducing-protein; DIP; dJ439F8.1; GRAM domain containing 4; GRAM domain-containing protein 4; GRAM domain-containing protein 4 (GRAMD4); Gramd4; Kiaa0767
Gene Symbols GRAMD4
Host Species Rabbit
Immunogen Recombinant Human GRAM domain-containing protein 4 protein (23-161AA).
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 223752, 23151
Target Species Human, Mouse
Content And Storage -20°C or -80°C if preferred
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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