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GRAMD4 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody
Supplier: Proteintech Group Inc 242991AP150UL

Description
GRAMD4 also termed as Death inducing protein is a 578 amino-acid protein, which contains 1 GRAM domain. GRAMD4 as a multi-pass membrane protein localizes in the Mitochondrion membrane. Overexpression of GRAMD4 results in a strong apoptotic response involving caspase-3 activation and cleavage of poly (ADP-ribose)-polymerase. GRAMD4 is expressed in lung and in primary lung squamous cell carcinoma (LSCC) and shows up-regulation in mitochondria by E2F-1 after addition of 4-hydroxytamoxifen. This evidence suggests that GRAMD4 may be a potential target for cancer therapies.Specifications
GRAMD4 | |
Polyclonal | |
Unconjugated | |
GRAMD4 | |
dA59H18.1, Death inducing protein, DIP, GRAM domain containing 4, GRAMD4, KIAA0767 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
23151 | |
-20°C | |
Liquid |
Western Blot | |
0.59 mg/mL | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
Q6IC98 | |
GRAMD4 | |
GRAMD4 Fusion Protein Ag19140 | |
150 μL | |
Primary | |
Human | |
Antibody | |
IgG |
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