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GRAMD4 Rabbit anti-Human, Polyclonal, Proteintech
SDP

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 242991AP150UL

Encompass_Preferred

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Catalog No. 50-173-4287


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Description

Description

GRAMD4 also termed as Death inducing protein is a 578 amino-acid protein, which contains 1 GRAM domain. GRAMD4 as a multi-pass membrane protein localizes in the Mitochondrion membrane. Overexpression of GRAMD4 results in a strong apoptotic response involving caspase-3 activation and cleavage of poly (ADP-ribose)-polymerase. GRAMD4 is expressed in lung and in primary lung squamous cell carcinoma (LSCC) and shows up-regulation in mitochondria by E2F-1 after addition of 4-hydroxytamoxifen. This evidence suggests that GRAMD4 may be a potential target for cancer therapies.
Specifications

Specifications

GRAMD4
Polyclonal
Unconjugated
GRAMD4
dA59H18.1, Death inducing protein, DIP, GRAM domain containing 4, GRAMD4, KIAA0767
Rabbit
Antigen Affinity Chromatography
RUO
23151
-20°C
Liquid
Western Blot
0.59 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q6IC98
GRAMD4
GRAMD4 Fusion Protein Ag19140
150 μL
Primary
Human
Antibody
IgG
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