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Invitrogen™ Grancalcin Polyclonal Antibody
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Catalog No. PIPA577127
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100 μL
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Catalog No. Quantity
PIPA577127 100 μL
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Catalog No. PIPA577127 Supplier Invitrogen™ Supplier No. PA577127
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Description

Rabbit Polyclonal Antibody

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).

This gene product, grancalcin, is a calcium-binding protein abundant in neutrophils and macrophages. It belongs to the penta-EF-hand subfamily of proteins which includes sorcin, calpain, and ALG-2. Grancalcin localization is dependent upon calcium and magnesium. In the absence of divalent cation, grancalcin localizes to the cytosolic fraction; with magnesium alone, it partitions with the granule fraction; and in the presence of magnesium and calcium, it associates with both the granule and membrane fractions, suggesting a role for grancalcin in granule-membrane fusion and degranulation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Grancalcin
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene Gca
Gene Accession No. P28676, Q8VC88
Gene Alias 5133401E04Rik; AI573844; Gca; GCL; grancalcin; grancalcin, EF-hand calcium binding protein; grancalcin, EF-hand calcium-binding protein; grancalcin, penta-EF-hand protein; null
Gene Symbols Gca
Host Species Rabbit
Immunogen Recombinant full length Human Grancalcin.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 227960, 25801
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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