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Invitrogen™ Granzyme A Monoclonal Antibody (356412)
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Catalog No. PIMA524105
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100 μg
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Catalog No. Quantity
PIMA524105 100 μg
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Catalog No. PIMA524105 Supplier Invitrogen™ Supplier No. MA524105
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Description

Mouse Monoclonal Antibody

In direct ELISAs, no cross-reactivity with recombinant human Granzyme B, C, D, G, or H is observed. Reconstitute at 0.5 mg/mL in sterile PBS.

Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here is a T cell- and natural killer cell-specific serine protease that may function as a common component necessary for lysis of target cells by cytotoxic T lymphocytes and natural killer cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Granzyme A
Applications Flow Cytometry, Immunoprecipitation, Immunocytochemistry
Classification Monoclonal
Clone 356412
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative; pH 7.4
Gene GZMA
Gene Accession No. P12544
Gene Alias Autocrine thymic lymphoma granzyme-like serine protease; AW494114; BLT esterase; CTL tryptase; CTLA3; CTLA-3; Cytotoxic T-lymphocyte proteinase 1; Cytotoxic T-lymphocyte-associated serine esterase-3; fragmentin-1; granzyme 1; granzyme A; Granzyme A (Cytotoxic T-lymphocyte-associated serine esterase-3; Hanukah factor serine protease); granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3); Granzyme-1; GZMA; H factor; Hanukah factor; Hanukah factor serine protease); Hanukkah factor; Hf; HFSP; Mtsp-1; SE1; serine esterase 1; t cell-specific serine protease 1; TSP1; TSP-1
Gene Symbols GZMA
Host Species Mouse
Immunogen Mouse myeloma cell line NS0-derived recombinant human Granzyme A Cys26-Val262.
Purification Method Protein A/G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3001
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG2b
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