Granzyme B Antibody

Rabbit Polyclonal Antibody

Supplier:  Novus Biologicals NB11059915

Catalog No. NB11059915

Description

Granzyme B Polyclonal antibody specifically detects Granzyme B in Human samples. It is validated for Immunohistochemistry, Immunohistochemistry (Paraffin).

Specifications

• Antigen: Granzyme B
• Classification: Polyclonal
• Dilution: Immunohistochemistry 1:10-1:500, Immunohistochemistry-Paraffin
• Gene Alias: C11, CCPI, CGL1, CGL-1, CSPB, CSP-B, CTLA1, CTSGL1, granzyme B, GranzymeB, GZMB, HLP, SECT
• Host Species: Rabbit
• Purification Method: Affinity purified
• Regulatory Status: RUO
• Gene ID (Entrez): 3002
• Target Species: Human, Mouse, Rat
• Form: Purified

• Applications: Immunohistochemistry, Immunohistochemistry (Paraffin)
• Conjugate: Unconjugated
• Formulation: PBS (pH 7.4), 0.2% BSA, Tween-20 with 0.05% Sodium Azide
• Gene Symbols: GZMB
• Immunogen: A synthetic peptide from the N-terminus of human Granzyme B.
• Quantity: 6 mL
• Primary or Secondary: Primary
• Test Specificity: This antibody reacts with a 32 kD protein. Granzymes are neutral serine proteases, which are stored in specialized lytic granules of cytotoxic T lymphocytes (CTLs) and in natural killer (NK) cells. A number of granzymes (A to G) have been isolated and cloned. Human granzymes B is involved in target cell apoptosis during lymphocyte-mediated cytotoxicity. This antibody is useful in the localization of granzyme B containing lytic granules and for the characterization of activated CTLs or NK cells. This antibody cross reacts with mouse and rat.
• Content And Storage: Store at 4°C.
• Isotype: IgG

For Research Use Only