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Granzyme B Antibody
SDP

Catalog No. NB11059915 Shop All R&D Systems Products
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NB11059915 6 mL
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Catalog No. NB11059915 Supplier Novus Biologicals Supplier No. NB11059915

Description

Rabbit Polyclonal Antibody

Granzyme B Polyclonal antibody specifically detects Granzyme B in Human samples. It is validated for Immunohistochemistry, Immunohistochemistry (Paraffin).

Specifications

Antigen Granzyme B
Applications Immunohistochemistry, Immunohistochemistry (Paraffin)
Classification Polyclonal
Conjugate Unconjugated
Dilution Immunohistochemistry 1:10-1:500, Immunohistochemistry-Paraffin
Formulation PBS (pH 7.4), 0.2% BSA, Tween-20 with 0.05% Sodium Azide
Gene Alias C11, CCPI, CGL1, CGL-1, CSPB, CSP-B, CTLA1, CTSGL1, granzyme B, GranzymeB, GZMB, HLP, SECT
Gene Symbols GZMB
Host Species Rabbit
Immunogen A synthetic peptide from the N-terminus of human Granzyme B.
Purification Method Affinity purified
Quantity 6 mL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3002
Test Specificity This antibody reacts with a 32 kD protein. Granzymes are neutral serine proteases, which are stored in specialized lytic granules of cytotoxic T lymphocytes (CTLs) and in natural killer (NK) cells. A number of granzymes (A to G) have been isolated and cloned. Human granzymes B is involved in target cell apoptosis during lymphocyte-mediated cytotoxicity. This antibody is useful in the localization of granzyme B containing lytic granules and for the characterization of activated CTLs or NK cells. This antibody cross reacts with mouse and rat.
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C.
Form Purified
Isotype IgG
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