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Invitrogen™ Granzyme H Polyclonal Antibody
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Catalog No. PIPA547129
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100 μg
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PIPA547129 100 μg
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Catalog No. PIPA547129 Supplier Invitrogen™ Supplier No. PA547129
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Description

Goat Polyclonal Antibody

This antibody detects both the pro and active forms of human Granzyme H in direct ELISAs and Western blots. In direct ELISAs, approximately 25% cross-reactivity with recombinant human Granzyme B is observed and approximately 5% cross-reactivity with recombinant mouse (rm) Granzyme C, rmGranzyme D, and rmGranzyme G is observed. Reconstitute at 0.2 mg/mL in sterile PBS. Endoxin level is <0.01 EU per 1 μg of the antibody by the LAL method.

This gene encodes a member of the peptidase S1 family of serine proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate a chymotrypsin-like protease. This protein is reported to be constitutively expressed in the NK (natural killer) cells of the immune system and may play a role in the cytotoxic arm of the innate immune response by inducing target cell death and by directly cleaving substrates in pathogen-infected cells. This gene is present in a gene cluster with another member of the granzyme subfamily on chromosome 14.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Granzyme H
Applications Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene GZMH
Gene Accession No. P20718
Gene Alias Cathepsin G-like 2; cathepsin G-like 2, protein h-CCPX; CCP-X; CGL2; CGL-2; CSP-C; CTLA1; CTSGL2; Cytotoxic serine protease C; Cytotoxic T-lymphocyte proteinase; cytotoxic T-lymphocyte-associated serine esterase 1; cytotoxin serine protease-C; granzyme H; granzyme H (cathepsin G-like 2, protein h-CCPX); GZMH
Gene Symbols GZMH
Host Species Goat
Immunogen Mouse myeloma cell line NS0-derived recombinant human Granzyme H Glu19-Leu246.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2999
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG
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