Invitrogen™ Granzyme H Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA583074

Catalog No. PIPA583074

Description

Immunogen sequence: HPAYNPKNFS NDIMLLQLER KAKWTTAVRP LRLPSSKAQV KPGQLCSVAG WGYVSMSTLA TTLQEVLLTV QKDCQCERLF HGNYSRATEI CVGDPKKTQT GFKGDSGGPL VCKDVAQGIL SYGNKKGTPP GVYIKVSHFL PWIKRTM.

This gene encodes a member of the peptidase S1 family of serine proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate a chymotrypsin-like protease. This protein is reported to be constitutively expressed in the NK (natural killer) cells of the immune system and may play a role in the cytotoxic arm of the innate immune response by inducing target cell death and by directly cleaving substrates in pathogen-infected cells. This gene is present in a gene cluster with another member of the granzyme subfamily on chromosome 14.

Specifications

• Antigen: Granzyme H
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GZMH
• Gene Alias: Cathepsin G-like 2; cathepsin G-like 2, protein h-CCPX; CCP-X; CGL2; CGL-2; CSP-C; CTLA1; CTSGL2; Cytotoxic serine protease C; Cytotoxic T-lymphocyte proteinase; cytotoxic T-lymphocyte-associated serine esterase 1; cytotoxin serine protease-C; granzyme H; granzyme H (cathepsin G-like 2, protein h-CCPX); GZMH
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2999
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P20718
• Gene Symbols: GZMH
• Immunogen: Recombinant protein corresponding to Human GZMH. Recombinant protein control fragment (Product #RP-88868).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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