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Invitrogen™ Granzyme H Polyclonal Antibody
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Catalog No. PIPA596522
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100 μL
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PIPA596522 100 μL
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Catalog No. PIPA596522 Supplier Invitrogen™ Supplier No. PA596522
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: EIIGGHEAKP HSRPYMAFVQ FLQEKSRKRC GGILVRKDFV LTAAHCQGSS INVTLGAHNI KEQERTQQFI PVKRPIPHPA YNPKNFSNDI MLLQLERKAK WTTAVRPLRL PSSKAQVKPG QLCSVAGWGY VSMSTLATTL QEVLLTVQKD CQCERLFHGN YSRATEICVG DPKKTQTGFK GDSGGPLVCK DVAQGILSYG NKKGTPPGVY IKVSHFLPWI KRTMKRL; Positive Samples: MCF7, Mouse spleen, Mouse liver; Cellular Location: Cytoplasmic granule.

This gene encodes a member of the peptidase S1 family of serine proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate a chymotrypsin-like protease. This protein is reported to be constitutively expressed in the NK (natural killer) cells of the immune system and may play a role in the cytotoxic arm of the innate immune response by inducing target cell death and by directly cleaving substrates in pathogen-infected cells. This gene is present in a gene cluster with another member of the granzyme subfamily on chromosome 14.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Granzyme H
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.19 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene GZMH
Gene Accession No. P20718
Gene Alias Cathepsin G-like 2; cathepsin G-like 2, protein h-CCPX; CCP-X; CGL2; CGL-2; CSP-C; CTLA1; CTSGL2; Cytotoxic serine protease C; Cytotoxic T-lymphocyte proteinase; cytotoxic T-lymphocyte-associated serine esterase 1; cytotoxin serine protease-C; granzyme H; granzyme H (cathepsin G-like 2, protein h-CCPX); GZMH
Gene Symbols GZMH
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 20-246 of human GZMH (NP_2194911).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2999
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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