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Invitrogen™ Granzyme K Monoclonal Antibody (C8), Invitrogen™

Catalog No. FEMA551116
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200 μL
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Catalog No. Quantity
FEMA551116 20 μL
FEMA551115 200 μL
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Catalog No. FEMA551116 Supplier Invitrogen™ Supplier No. MA551116
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Description

Mouse Monoclonal Antibody

Granzyme K (GrK) belongs to a family of trypsin-like serine proteases localised in the cytotoxic granules of activated T cells and NK cells. It encodes a 28 kDa serine protease whose gene is located on chromosome 5q11-12 close to the granzyme A-encoding gene. Like granzyme A, it has a trypsin-like specifity cleaving at the basic residues arginine and lysine. Granzyme K triggers rapid cell death independently of caspase activation with single-stranded DNA nicks and is primarily expressed in thymus, lung, spleen and peripheral blood leukocytes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Granzyme K
Applications Western Blot
Classification Monoclonal
Clone C8
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% Proclin 300; pH 7.4
Gene GZMK
Gene Accession No. O35205, P49864
Gene Alias Fragmentin-3; granzyme 3; granzyme K; granzyme K (granzyme 3; tryptase II); granzyme K (serine protease, granzyme 3; tryptase II); granzyme-3; GrK; GZMK; NK-Tryp-2; NK-tryptase-2; RNK-Tryp-2; TRYP2; tryptase II
Gene Symbols GZMK
Host Species Mouse
Immunogen Recombinant Mouse GZMK protein, Gln44-Val227 (Accession #O35205).
Purification Method Protein A/G
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14945, 29165
Target Species Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2b κ
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