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Granzyme K Monoclonal Antibody (GM24C3), Invitrogen™

Catalog No. 01670166
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100 μg
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Catalog No. Quantity
01-670-166 100 μg
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Catalog No. 01-670-166 Supplier Thermo Scientific Supplier No. MA117753

Item Discontinued This product is either new or inactive, and cannot be ordered online.

Description

Mouse Monoclonal Antibody

This antibody recognizes native Granzyme K protein expressed in transfected mammalian cells.

Granzyme K (GrK) belongs to a family of trypsin-like serine proteases localised in the cytotoxic granules of activated T cells and NK cells. It encodes a 28 kDa serine protease whose gene is located on chromosome 5q11-12 close to the granzyme A-encoding gene. Like granzyme A, it has a trypsin-like specifity cleaving at the basic residues arginine and lysine. Granzyme K triggers rapid cell death independently of caspase activation with single-stranded DNA nicks and is primarily expressed in thymus, lung, spleen and peripheral blood leukocytes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Granzyme K
Applications ELISA, Flow Cytometry
Classification Monoclonal
Clone GM24C3
Conjugate Unconjugated
Formulation PBS with no preservative; pH 7.2
Gene GZMK
Gene Accession No. P49863
Gene Alias Fragmentin-3; granzyme 3; granzyme K; granzyme K (granzyme 3; tryptase II); granzyme K (serine protease, granzyme 3; tryptase II); granzyme-3; GrK; GZMK; NK-Tryp-2; NK-tryptase-2; RNK-Tryp-2; TRYP2; tryptase II
Gene Symbols GZMK
Host Species Mouse
Immunogen cDNA encoding human Granzyme K
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3003
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2b
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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