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Granzyme K Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA550980

Catalog No. PA550980


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Description

Description

Granzyme K Polyclonal Antibody detects endogenous levels of Granzyme K protein.

Granzyme K (GrK) belongs to a family of trypsin-like serine proteases localised in the cytotoxic granules of activated T cells and NK cells. It encodes a 28 kDa serine protease whose gene is located on chromosome 5q11-12 close to the granzyme A-encoding gene. Like granzyme A, it has a trypsin-like specifity cleaving at the basic residues arginine and lysine. Granzyme K triggers rapid cell death independently of caspase activation with single-stranded DNA nicks and is primarily expressed in thymus, lung, spleen and peripheral blood leukocytes.
Specifications

Specifications

Granzyme K
Polyclonal
Unconjugated
GZMK
Liquid
GZMK
Synthesized peptide derived from the Internal region of human Granzyme K.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
1 mg/mL
PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4
P49863, O35205, P49864
GrK
Rabbit
IgG
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
14945, 29165, 3003
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