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Invitrogen™ GRASP1 Polyclonal Antibody
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Catalog No. PA549679
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100 μL
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Catalog No. Quantity
PA549679 100 μL
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Catalog No. PA549679 Supplier Invitrogen™ Supplier No. PA549679
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Description

Rabbit Polyclonal Antibody

The antibody detects endogenous level of total GRIP1 protein.

PDZ domain-containing proteins, such as PSD-95 and GRIP are thought to play key roles in glutamate receptor plasticity. GRIP-associated proteins (GRASPs) that bind to distinct PDZ domains within GRIP also play key roles in regulation of glutamate receptor function. GRASP-1 is a neuronal rasGEF associated with GRIP and AMPA receptors in vivo (Scannevin and Huganir, 2000). Recent work suggests that GRASP-1 may regulate neuronal ras signaling and contribute to the regulation of AMPA receptor distribution by NMDA receptor activity (Ye et al., 2000).
TRUSTED_SUSTAINABILITY

Specifications

Antigen GRASP1
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene GRIPAP1
Gene Accession No. Q4V328, Q8VD04, Q9JHZ4
Gene Alias 30kDa C-terminus form; AI854681; DXImx47e; Grasp1; GRASP-1; GRASP-1 C-terminal chain; GRIP1; GRIP-1; GRIP1 associated protein 1; GRIP1-associated protein 1; Gripap1; GRIP-associated protein 1; HCMV-interacting protein; Kiaa1167; mKIAA1167; MPMGp800B12492Q3; Sfc10
Gene Symbols GRIPAP1
Host Species Rabbit
Immunogen Peptide sequence around aa. 814-818(Q-E-I-V-R ) derived from Rat GRASP.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 116493, 54645, 56850
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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