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Invitrogen™ GRB10 Monoclonal Antibody (5H7)
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Catalog No. PIMA549206
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100 μg
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PIMA549206 100 μg
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Catalog No. PIMA549206 Supplier Invitrogen™ Supplier No. MA549206
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Mouse Monoclonal Antibody

Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL. Positive Control - WB: human Hek293 whole cell, human Hela whole cell, monkey COS-7 whole cell, human HepG2 whole cell, rat kidney tissue, rat NRK whole cell. Flow: THP-1 cell. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

GRB7, a SH2 domain protein, has a single SH2 domain at its C-terminal, a central region with similarity to Ras GAP, and a proline-rich N terminus. A related SH2 domain-containing protein, GRB10, exhibits a high degree of homology with GRB7. GRB10 undergoes serine but not tyrosine phosphorylation in response to EGF treatment, but appears to bind to the EGF receptor poorly. GRB10 maps to mouse chromosome 11, in close proximity to the EGF receptor. Similarly, GRB7 maps to the same mouse chromosome near the EGF receptor-related protein HER2.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GRB10
Applications Flow Cytometry, Western Blot
Classification Monoclonal
Clone 5H7
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 4mg trehalose and no preservative
Gene GRB10
Gene Accession No. P0CE43, Q13322
Gene Alias 5730571D09Rik; AI325020; Grb10; Grb-10; GRB10 adapter protein; GRB10 adaptor protein; GRBIR; GRB-IR; growth factor receptor bound protein 10; growth factor receptor-bound protein 10; Insulin receptor-binding protein Grb-IR; IRBP; KIAA0207; maternally expressed gene 1; maternally expressed gene 1 protein; Meg1; mKIAA0207; OTTHUMP00000197988; OTTHUMP00000197989; OTTHUMP00000197990; OTTHUMP00000197991; OTTHUMP00000197993; OTTHUMP00000197994; RGD1566234; RSS
Gene Symbols GRB10
Host Species Mouse
Immunogen E.coli-derived human GRB10 recombinant protein (Position: M1-K251).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2887, 498416
Target Species Human, Monkey, Rat
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG1
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