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Invitrogen™ GRB10 Polyclonal Antibody
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Catalog No. PIPA532240
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100 μL
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PIPA532240 100 μL
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Catalog No. PIPA532240 Supplier Invitrogen™ Supplier No. PA532240
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: HepG2. Predicted reactivity: Mouse (89%), Rat (90%), Pig (97%), Chicken (94%), Rhesus Monkey (100%), Bovine (97%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

GRB7, a SH2 domain protein, has a single SH2 domain at its C-terminal, a central region with similarity to Ras GAP, and a proline-rich N terminus. A related SH2 domain-containing protein, GRB10, exhibits a high degree of homology with GRB7. GRB10 undergoes serine but not tyrosine phosphorylation in response to EGF treatment, but appears to bind to the EGF receptor poorly. GRB10 maps to mouse chromosome 11, in close proximity to the EGF receptor. Similarly, GRB7 maps to the same mouse chromosome near the EGF receptor-related protein HER2.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GRB10
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gene GRB10
Gene Accession No. Q13322
Gene Alias 5730571D09Rik; AI325020; Grb10; Grb-10; GRB10 adapter protein; GRB10 adaptor protein; GRBIR; GRB-IR; growth factor receptor bound protein 10; growth factor receptor-bound protein 10; Insulin receptor-binding protein Grb-IR; IRBP; KIAA0207; maternally expressed gene 1; maternally expressed gene 1 protein; Meg1; mKIAA0207; OTTHUMP00000197988; OTTHUMP00000197989; OTTHUMP00000197990; OTTHUMP00000197991; OTTHUMP00000197993; OTTHUMP00000197994; RGD1566234; RSS
Gene Symbols GRB10
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the C-terminus region of human GRB10. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2887
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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