Invitrogen™ GRB10 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA599633

Catalog No. PIPA599633

Description

Antibody detects endogenous levels of total GRB10.

GRB7, a SH2 domain protein, has a single SH2 domain at its C-terminal, a central region with similarity to Ras GAP, and a proline-rich N terminus. A related SH2 domain-containing protein, GRB10, exhibits a high degree of homology with GRB7. GRB10 undergoes serine but not tyrosine phosphorylation in response to EGF treatment, but appears to bind to the EGF receptor poorly. GRB10 maps to mouse chromosome 11, in close proximity to the EGF receptor. Similarly, GRB7 maps to the same mouse chromosome near the EGF receptor-related protein HER2.

Specifications

• Antigen: GRB10
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GRB10
• Gene Alias: 5730571D09Rik; AI325020; Grb10; Grb-10; GRB10 adapter protein; GRB10 adaptor protein; GRBIR; GRB-IR; growth factor receptor bound protein 10; growth factor receptor-bound protein 10; Insulin receptor-binding protein Grb-IR; IRBP; KIAA0207; maternally expressed gene 1; maternally expressed gene 1 protein; Meg1; mKIAA0207; OTTHUMP00000197988; OTTHUMP00000197989; OTTHUMP00000197990; OTTHUMP00000197991; OTTHUMP00000197993; OTTHUMP00000197994; RGD1566234; RSS
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2887
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q13322
• Gene Symbols: GRB10
• Immunogen: A synthesized peptide derived from human GRB10(Accession Q13322), corresponding to amino acid residues N406-L456.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG