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GRB2 Monoclonal Antibody (2GB04 (C1.4)), Invitrogen™

Catalog No. PIMA512165
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500 μL
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Catalog No. Quantity
PIMA512165 500 μL
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Catalog No. PIMA512165 Supplier Thermo Scientific Supplier No. MA512165
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Description

Mouse Monoclonal Antibody

MA5-12165 targets Grb2 in IF and IHC (P) applications and shows reactivity with Bovine, Human, mouse, Rat, and Xenopus laevis samples. The MA5-12165 immunogen is purified recombinant human Grb2 protein.

GRB 2 protein contains one SH2 domain flanked on both sides by an SH3 domain. In response to EGF, GRB 2 binds, through its SH3 domains, to the guanine nucleotide exchange factor, Sos. The GRB 2-Sos complex then binds the EGF receptor. These interactions play a critical role in the activation of the p21 ras signaling pathway.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GRB2
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone 2GB04 (C1.4)
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene GRB2
Gene Accession No. P62993, P62994, P87379, Q60631
Gene Alias AA408164; abundant SRC homology; adapter protein GRB2; Adapter protein GRB2-A; ASH; ASH protein; EGFRBP-GRB2; epidermal growth factor receptor-binding protein GRB2; grb2; grb2.L; grb2-a; grb2-b; Grb3-3; growth factor receptor bound protein 2; growth factor receptor bound protein 2 L homeolog; growth factor receptor-bound protein 2; Growth factor receptor-bound protein 2-A; growth factor receptor-bound protein 3; HT027; hypothetical protein LOC535298; MST084; MSTP084; NCKAP2; OTTHUMP00000166097; OTTHUMP00000166098; protein Ash; SH2/SH3 adapter GRB2; SH2/SH3 adapter GRB2-A; SH2/SH3 adaptor Grb2; XELAEV_18044055mg
Gene Symbols GRB2, grb2.L
Host Species Mouse
Immunogen Purified recombinant human Grb2 protein
Purification Method Protein G
Quantity 500 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14784, 2885, 399458, 535298, 81504
Target Species Bovine, Human, Mouse, Rat, X. laevis
Content And Storage 4° C
Form Liquid
Isotype IgG1 κ
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