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Invitrogen™ GRB2 Polyclonal Antibody
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Catalog No. PIPA517692
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100 μL
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PIPA517692 100 μL
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Catalog No. PIPA517692 Supplier Invitrogen™ Supplier No. PA517692
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Description

Rabbit Polyclonal Antibody

It is not recommended to aliquot this antibody.

GRB 2 protein contains one SH2 domain flanked on both sides by an SH3 domain. In response to EGF, GRB 2 binds, through its SH3 domains, to the guanine nucleotide exchange factor, Sos. The GRB 2-Sos complex then binds the EGF receptor. These interactions play a critical role in the activation of the p21 ras signaling pathway.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GRB2
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 217 μg/mL
Conjugate Unconjugated
Formulation 0.01M HEPES with 100μg/mL BSA, 50% glycerol, 0.15M NaCl and no preservative; pH 7.5
Gene GRB2
Gene Accession No. P62993, P62994, Q60631
Gene Alias AA408164; abundant SRC homology; adapter protein GRB2; Adapter protein GRB2-A; ASH; ASH protein; EGFRBP-GRB2; epidermal growth factor receptor-binding protein GRB2; grb2; grb2.L; grb2-a; grb2-b; Grb3-3; growth factor receptor bound protein 2; growth factor receptor bound protein 2 L homeolog; growth factor receptor-bound protein 2; Growth factor receptor-bound protein 2-A; growth factor receptor-bound protein 3; HT027; hypothetical protein LOC535298; MST084; MSTP084; NCKAP2; OTTHUMP00000166097; OTTHUMP00000166098; protein Ash; SH2/SH3 adapter GRB2; SH2/SH3 adapter GRB2-A; SH2/SH3 adaptor Grb2; XELAEV_18044055mg
Gene Symbols GRB2
Host Species Rabbit
Immunogen Synthetic peptide corresponding to carboxy-terminal residues of human GRB2.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100769627, 14784, 2885, 535298, 81504
Target Species Human, Mouse, Rat, Monkey, Bovine, Hamster
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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