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Invitrogen™ GRB2 Polyclonal Antibody
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Catalog No. PIPA131495
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50 μg
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PIPA131495 50 μg
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Catalog No. PIPA131495 Supplier Invitrogen™ Supplier No. PA131495
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Description

Goat Polyclonal Antibody

Recommended positive controls: The peptide used to generate this antibody is available for purchase (GTX22234-PEP).. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

GRB 2 protein contains one SH2 domain flanked on both sides by an SH3 domain. In response to EGF, GRB 2 binds, through its SH3 domains, to the guanine nucleotide exchange factor, Sos. The GRB 2-Sos complex then binds the EGF receptor. These interactions play a critical role in the activation of the p21 ras signaling pathway.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GRB2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene GRB2
Gene Accession No. P62993, P62994, Q60631
Gene Alias AA408164; abundant SRC homology; adapter protein GRB2; Adapter protein GRB2-A; ASH; ASH protein; EGFRBP-GRB2; epidermal growth factor receptor-binding protein GRB2; grb2; grb2.L; grb2-a; grb2-b; Grb3-3; growth factor receptor bound protein 2; growth factor receptor bound protein 2 L homeolog; growth factor receptor-bound protein 2; Growth factor receptor-bound protein 2-A; growth factor receptor-bound protein 3; HT027; hypothetical protein LOC535298; MST084; MSTP084; NCKAP2; OTTHUMP00000166097; OTTHUMP00000166098; protein Ash; SH2/SH3 adapter GRB2; SH2/SH3 adapter GRB2-A; SH2/SH3 adaptor Grb2; XELAEV_18044055mg
Gene Symbols GRB2
Host Species Goat
Immunogen Peptide with sequence C-PRNYVTPVNRNV, from the C Terminus.
Purification Method Antigen affinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100192436, 14784, 2885, 81504
Target Species Human, Mouse, Rat, Pig
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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