Invitrogen™ GRB7 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5102994

Catalog No. PIPA5102994

Description

Antibody detects endogenous levels of total GRB7.

The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with epidermal growth factor receptor (EGFR) and ephrin receptors. The protein plays a role in the integrin signaling pathway and cell migration by binding with focal adhesion kinase (FAK). Alternative splicing results in multiple transcript variants encoding different isoforms, although the full-length natures of only two of the variants have been determined to date.

Specifications

• Antigen: GRB7
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GRB7
• Gene Alias: B47; Epidermal growth factor receptor GRB-7; Grb7; GRB7 adapter protein; growth factor receptor binding protein GRB7; growth factor receptor bound protein 7; growth factor receptor-bound protein 7; Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7); mKIAA4028; OTTHUMP00000164352
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2886, 84427
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q14451, Q9QZC5
• Gene Symbols: GRB7
• Immunogen: A synthesized peptide derived from human GRB7(Accession Q14451), corresponding to amino acid residues V286-F336.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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