Invitrogen™ GREM1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA570341

Catalog No. PIPA570341

Description

This target displays homology in the following species: Cow: 92%; Dog: 100%; Goat: 92%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 92%; Rat: 100%; Zebrafish: 93%.

In Xenopus, Gremlin belongs to a novel gene family that act as BMP antagonists in embryonic explants. The human homolog of Drm/Gremlin (CKTFS1B1) is localized on human chromosome 15q13--> q15. DRM-specific mRNA is expressed in different human tissues, including brain, ovary, intestine and colon. It has been suggested that down-regulation of DRM is associated with tumor progression, and support the hypothesis that human DRM may play an important role during both neuroembryological development and carcinogenesis.

Specifications

• Antigen: GREM1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Grem1
• Gene Alias: C15DUPq; Cell proliferation-inducing gene 2 protein; CKTSF1B1; colorectal adenoma and carcinoma 1; CRAC1; CRCS4; Cysteine knot superfamily 1, BMP antagonist 1; DAN domain family member 2; DAND2; Down-regulated in Mos-transformed cells protein; down-regulated in v-mos-transformed cells; Drm; DUP15q; Grem; GREM1; gremlin; gremlin 1; gremlin 1 homolog, cysteine knot superfamily; gremlin 1, cysteine knot superfamily, homolog; gremlin 1, DAN family BMP antagonist; gremlin 1-like protein; gremlin-1; HMPS; HMPS1; IHG-2; Increased in high glucose protein 2; increased in high glucose-2; ld; MPSH; PIG2
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23892, 50566
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: O35793, O70326
• Gene Symbols: Grem1
• Immunogen: synthetic peptide directed towards the middle region of rat GREM1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov