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Invitrogen™ GREM2 Polyclonal Antibody
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Catalog No. PIPA578559
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100 μL
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PIPA578559 100 μL
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Catalog No. PIPA578559 Supplier Invitrogen™ Supplier No. PA578559
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Description

Rabbit Polyclonal Antibody

Positive Control: A549, IMR32 Predicted Reactivity: Mouse (100%), Rat (100%), Rhesus Monkey (100%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

GREM2 encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GREM2
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.15 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Grem2
Gene Accession No. Q9H772
Gene Alias CKTSF1B2; CKTSF1B2FLJ21195; Cysteine knot superfamily 1, BMP antagonist 2; DAN domain family member 3; DAND3; DAND3Prdc; GREM2; gremlin 2; gremlin 2 homolog, cysteine knot superfamily; gremlin 2 homolog, cysteine knot superfamily (Xenopus laevis); gremlin 2, cysteine knot superfamily, homolog; gremlin 2, DAN family BMP antagonist; Gremlin1; Gremlin2; gremlin-2; Prdc; PRDCgremlin 2; Protein related to DAN and cerberus; RGD1560008
Gene Symbols Grem2
Host Species Rabbit
Immunogen Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human GREM2. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 64388
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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