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Invitrogen™ GREM2 Polyclonal Antibody
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Catalog No. PIPA5119878
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100 μL
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PIPA5119878 100 μL
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Catalog No. PIPA5119878 Supplier Invitrogen™ Supplier No. PA5119878
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Description

Rabbit Polyclonal Antibody

Positive Control: CAL62 cell lysates, SH-SY5Y. Subcellular Location: Secreted.

GREM2 encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GREM2
Applications Flow Cytometry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene Grem2
Gene Accession No. Q9H772
Gene Alias CKTSF1B2; CKTSF1B2FLJ21195; Cysteine knot superfamily 1, BMP antagonist 2; DAN domain family member 3; DAND3; DAND3Prdc; GREM2; gremlin 2; gremlin 2 homolog, cysteine knot superfamily; gremlin 2 homolog, cysteine knot superfamily (Xenopus laevis); gremlin 2, cysteine knot superfamily, homolog; gremlin 2, DAN family BMP antagonist; Gremlin1; Gremlin2; gremlin-2; Prdc; PRDCgremlin 2; Protein related to DAN and cerberus; RGD1560008
Gene Symbols Grem2
Host Species Rabbit
Immunogen Synthetic peptide within human PRDC aa 50-100.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 64388
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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