Invitrogen™ GREM2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA578559

Catalog No. PIPA578559

Description

Positive Control: A549, IMR32 Predicted Reactivity: Mouse (100%), Rat (100%), Rhesus Monkey (100%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

GREM2 encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation.

Specifications

• Antigen: GREM2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Grem2
• Gene Alias: CKTSF1B2; CKTSF1B2FLJ21195; Cysteine knot superfamily 1, BMP antagonist 2; DAN domain family member 3; DAND3; DAND3Prdc; GREM2; gremlin 2; gremlin 2 homolog, cysteine knot superfamily; gremlin 2 homolog, cysteine knot superfamily (Xenopus laevis); gremlin 2, cysteine knot superfamily, homolog; gremlin 2, DAN family BMP antagonist; Gremlin1; Gremlin2; gremlin-2; Prdc; PRDCgremlin 2; Protein related to DAN and cerberus; RGD1560008
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 64388
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1.26 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: Q9H772
• Gene Symbols: Grem2
• Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human GREM2. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG