Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. PIPA579329

Invitrogen™ GRIK1 Polyclonal Antibody
GREENER_CHOICE

Catalog No. PIPA579329
Change view
Click to view available options
Quantity:
100 μg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
PIPA579329 100 μg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. PIPA579329 Supplier Invitrogen™ Supplier No. PA579329
Add to Cart
Add to Cart

Description

Rabbit Polyclonal Antibody

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: mouse brain tissue, mouse brain tissue, human SHG whole cell, rat brain tissue, mouse brain tissue. IHC: human glioma tissue, human Lung cancer tissue, human thyroid cancer tissue, mouse brain tissue.

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. Grik1, also known as glutamate receptor 5, belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. Grik1 is expressed in GABAergic interneurons of the hippocampus and are thought to participate in the formation of various subtypes of kainate receptors with Grik2 and KA2. Stimulation of Grik1 leads to intracellular calcium release and activation of protein kinase C. Excessive activation has been associated with psychiatric, neurological and neurodegenerative diseases. Numerous isoforms of Grik1 are known to exist and may be subject to RNA editing within the second transmembrane domain, which is thought to alter the properties of ion flow.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GRIK1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 5mg BSA and 0.05mg sodium azide
Gene Grik1
Gene Accession No. P22756, P39086, Q60934
Gene Alias A830007B11Rik; D16Ium24; D16Ium24e; EAA3; EEA3; excitatory amino acid receptor 3; GLR5; GluK1; GluK5; GLUR5; gluR-5; Glurbeta1; glutamate ionotropic receptor kainate type subunit 1; glutamate receptor; glutamate receptor 5; Glutamate receptor ionotropic, kainate 1; glutamate receptor subunit 5; glutamate receptor, ionotropic, kainate 1; GRIK1
Gene Symbols Grik1
Host Species Rabbit
Immunogen E.coli-derived human GRIK1 recombinant protein (Position: R271-I450).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14805, 2897, 29559
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG
Show More Show Less

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.