GRIK5/KA2 Rabbit anti-Human, Polyclonal, Bioss

Rabbit Polyclonal Antibody

Supplier:  Bioss BS12033R

Catalog No. 50-198-1887

Description

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. Grik5, also known as kainate-preferring glutamate recptor subunit KA2, belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. Grik5 is highly homologous to the related ionotrophic glutamate receptor Grik4 (also known as KA1). Like Grik4, Grik5 does not form homomeric channels, but instead forms heteromers with Grik2. In Grik2- but not Grik1-null mice, Grik5 surface expression is greatly reduced in neurons, indicating that Grik2/Grik5 heteromers are required for exit from the endoplasmic reticulum to the cell surface.

Specifications

• Antigen: GRIK5/KA2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GRIK5
• Gene Alias: BOS_17702; EAA2; Excitatory amino acid receptor 2; GluK5; GluR gamma-2; GluRgamma2; glutamate ionotropic receptor kainate type subunit 5; Glutamate receptor gamma-2; Glutamate receptor ionotropic, kainate 5; glutamate receptor KA2; Glutamate receptor KA-2; glutamate receptor, ionotropic kainate 5; glutamate receptor, ionotropic, kainate 5; glutamate receptor, ionotropic, kainate 5 (gamma 2); GRIK2; Grik5; iGlu5; KA2; LOW QUALITY PROTEIN: glutamate receptor ionotropic, kainate 5
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 2901
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 μg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene Accession No.: Q16478
• Gene Symbols: GRIK5
• Immunogen: KLH conjugated synthetic peptide derived from human GRIK5/KA2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG