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Invitrogen™ GRIK5 Polyclonal Antibody
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Catalog No. PIPA599816
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100 μL
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PIPA599816 100 μL
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Catalog No. PIPA599816 Supplier Invitrogen™ Supplier No. PA599816
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total GRIK5.

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. Grik5, also known as kainate-preferring glutamate recptor subunit KA2, belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. Grik5 is highly homologous to the related ionotrophic glutamate receptor Grik4 (also known as KA1). Like Grik4, Grik5 does not form homomeric channels, but instead forms heteromers with Grik2. In Grik2- but not Grik1-null mice, Grik5 surface expression is greatly reduced in neurons, indicating that Grik2/Grik5 heteromers are required for exit from the endoplasmic reticulum to the cell surface.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GRIK5
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene GRIK5
Gene Accession No. Q16478
Gene Alias EAA2; Excitatory amino acid receptor 2; GluK5; GluR gamma-2; GluRgamma2; glutamate ionotropic receptor kainate type subunit 5; glutamate receptor; glutamate receptor gamma-2; Glutamate receptor ionotropic, kainate 5; glutamate receptor KA2; glutamate receptor KA-2; glutamate receptor, ionotropic kainate 5; glutamate receptor, ionotropic, kainate 5; glutamate receptor, ionotropic, kainate 5 (gamma 2); GRIK2; GRIK5; iGlu5; KA2; LOW QUALITY PROTEIN: glutamate receptor ionotropic, kainate 5; MGC128958 protein
Gene Symbols GRIK5
Host Species Rabbit
Immunogen A synthesized peptide derived from human GRIK5(Accession Q16478), corresponding to amino acid residues V448-A498.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2901
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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