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Invitrogen™ GRIK5 Polyclonal Antibody
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Catalog No. PIPA520451
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100 μg
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Catalog No. Quantity
PIPA520451 100 μg
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Catalog No. PIPA520451 Supplier Invitrogen™ Supplier No. PA520451
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Description

Rabbit Polyclonal Antibody

A suggested positive control is human brain tissue lysate. PA5-20451 can be used with blocking peptide PEP-0568.

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. Grik5, also known as kainate-preferring glutamate recptor subunit KA2, belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. Grik5 is highly homologous to the related ionotrophic glutamate receptor Grik4 (also known as KA1). Like Grik4, Grik5 does not form homomeric channels, but instead forms heteromers with Grik2. In Grik2- but not Grik1-null mice, Grik5 surface expression is greatly reduced in neurons, indicating that Grik2/Grik5 heteromers are required for exit from the endoplasmic reticulum to the cell surface.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GRIK5
Applications Immunohistochemistry, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene GRIK5
Gene Accession No. Q16478, Q61626, Q63273
Gene Alias EAA2; Excitatory amino acid receptor 2; GluK5; GluR gamma-2; GluRgamma2; glutamate ionotropic receptor kainate type subunit 5; glutamate receptor; glutamate receptor gamma-2; Glutamate receptor ionotropic, kainate 5; glutamate receptor KA2; glutamate receptor KA-2; glutamate receptor, ionotropic kainate 5; glutamate receptor, ionotropic, kainate 5; glutamate receptor, ionotropic, kainate 5 (gamma 2); GRIK2; GRIK5; iGlu5; KA2; LOW QUALITY PROTEIN: glutamate receptor ionotropic, kainate 5; MGC128958 protein
Gene Symbols GRIK5
Host Species Rabbit
Immunogen A 17 amino acid peptide near the carboxy terminus of the human Grik5.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14809, 24407, 2901
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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