GRK1 Monoclonal Antibody (OTI1E11), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA811854

Catalog No. 50-168-4293

Description

The sensation of sight is the result of a cascade of events starting with the interaction of photoactivated rhodopsin with a protein called transducin. Rhodopsin kinase is a G-protein-coupled Ser/Thr kinase, also known as GRK1, which is a key element in the regulation of this cascade. Following phosphorylation by GRK1, arrestin is recruited to phospho-rhodopsin quenching its phototransductive activity by preventing further interaction with transducin. By breaking the cycle of phototransduction, GRK1 plays an important role in the restoration of the system for subsequent visual events.

Specifications

• Antigen: GRK1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q15835
• Gene Symbols: GRK1
• Immunogen: Full length human recombit protein of human GRK1 produced in HEK293T cell.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot
• Clone: OTI1E11
• Conjugate: Unconjugated
• Gene: GRK1
• Gene Alias: GPRK1, RHOK, RK
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 6011
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid