Invitrogen™ GRK3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA527718

Catalog No. PIPA527718

Description

Recommended positive controls: HeLa, Molt-4. Predicted reactivity: Mouse (92%), Rat (92%), Bovine (95%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

ADRBK2, or adrenergic beta receptor kinase 2 is a serine/threonine kinase that is thought to act as a regulator of receptor function. Overall, the ADRBK2 enzyme, also known as GRK3, has 85% amino acid similarity with ADRBK1, with the protein kinase catalytic domain having 95% similarity. The ADRBK2 mRNA is approximately 8 kilobases with a distribution similar to that of ADRBK1. These data suggest the existence of a family of receptor kinases which may serve broadly to regulate receptor function.

Specifications

• Antigen: GRK3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GRK3
• Gene Alias: 4833444A01Rik; ADRBK2; Adrbk-2; adrenergic receptor kinase, beta 2; adrenergic receptor kinase, beta 2 (G-protein-linked receptor kinase); adrenergic, beta, receptor kinase 2; AI851927; AW551196; BARK2; Bark-2; beta ARK2; beta-adrenergic receptor kinase 2; Beta-ARK-2; G protein-coupled receptor kinase 3; G-protein-coupled receptor kinase 3; Grk3
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 157
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.63 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P35626
• Gene Symbols: GRK3
• Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 225 of Human GRK3.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov