Invitrogen™ GRK3 Recombinant Rabbit Monoclonal Antibody (10O6S3)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA542913

Catalog No. PIMA542913

Description

Positive test controls include: Jurkat, SH-SY5Y. Immunogen sequence: EWRGEGESRQ NLLTMEQILS VEETQIKDKK CILFRIKGGK QFVLQCESDP EFVQWKKELN ETFKEAQRLL RRAPKFLNKP RSGTVELPKP SLCHRNSNGL.

ADRBK2, or adrenergic beta receptor kinase 2 is a serine/threonine kinase that is thought to act as a regulator of receptor function. Overall, the ADRBK2 enzyme, also known as GRK3, has 85% amino acid similarity with ADRBK1, with the protein kinase catalytic domain having 95% similarity. The ADRBK2 mRNA is approximately 8 kilobases with a distribution similar to that of ADRBK1. These data suggest the existence of a family of receptor kinases which may serve broadly to regulate receptor function.

Specifications

• Antigen: GRK3
• Classification: Recombinant Monoclonal
• Concentration: 0.45 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P35626
• Gene Symbols: GRK3
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 589-688 of human GRK3 (P35626).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Western Blot
• Clone: 10O6S3
• Conjugate: Unconjugated
• Gene: GRK3
• Gene Alias: 4833444A01Rik; ADRBK2; Adrbk-2; adrenergic receptor kinase, beta 2; adrenergic receptor kinase, beta 2 (G-protein-linked receptor kinase); adrenergic, beta, receptor kinase 2; AI851927; AW551196; BARK2; Bark-2; beta ARK2; beta-adrenergic receptor kinase 2; Beta-ARK-2; G protein-coupled receptor kinase 3; G-protein-coupled receptor kinase 3; Grk3
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 157
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov